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Table 2 Xenotransplantation of cells into NOD/SCID mice

From: Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma

Cells + Treatment

Inoculum size

Tumor incidence

Tumor volume (mm3)

ACHN

cell line

Caki-1

cell line

ACHN

cell line

Caki-1

cell line

Parental cells

1 × 105

6/6

6/6

  

1 × 104

4/6

5/6

501.17 ± 46.31

544.67 ± 62.26

1 × 103

1/6

1/6

  

CSCs

1 × 105

6/6

6/6

  

1 × 104

6/6

6/6

774.67 ± 54.04

756.67 ± 70.32

1 × 103

3/6

3/6

  

CSCs + MRK003

1 × 105

5/6

5/6

  

1 × 104

2/6

3/6

306.17 ± 56.56

378.50 ± 38.34

1 × 103

0/6

1/6

  

CSCs + Numb

1 × 105

5/6

5/6

  

1 × 104

3/6

3/6

317.17 ± 82.34

377.50 ± 51.93

1 × 103

0/6

1/6

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