Fig. 4
Proliferation capacity of melanoma cells was suppressed by (Arg)9-GST SH2 TrM. a Representative images of colony formation assay showing colonies formed by B16F10 cells incubated with (Arg)9-GST SH2 TrM or (Arg)9-GST (n = 3, *P < 0.05). b (Arg)9-GST SH2 TrM treatment blocked the EGFR-Grb2 signaling of B16F10 cells. IP, immunoprecipitation; IB, immunoblot. WCL, whole cell lysates. c (Arg)9-GST SH2 TrM treatment reduced the phosphorylation of ERK and AKT of B16F10 cells. Data shown are representative of three independent experiments