From: TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness
Pathway name and status in A375 vs SK-Mel-28 | GEO Analysis (Affymetrix) | ||
---|---|---|---|
biopsy of melanomas (n = 45) | biopsy of nevi (n = 18) | t test (melanomas vs nevi) | |
TIMP3 (Down-regulated, Illumina) | 81.64 ± 9.1 | 92.56 ± 7.23 | p value 0.00006 |
IL1RA (Down-regulated, Luminex) | 60.02 ± 13.34 | 73.89 ± 12.15 | p value 0.00029 |
VEGFA (Up-regulated, Luminex) | 79.31 ± 12.39 | 60.78 ± 18.15 | p value 0.00132 |