From: Targeted radiotherapy of pigmented melanoma with 131I-5-IPN
 | B16F10 melanoma (n = 5) | Blocked B16F10 melanoma (n = 5) | A375 melanoma (n = 5) | ||||
---|---|---|---|---|---|---|---|
1 h | 6 h | 24 h | 48 h | 72 h | 1 h | 1 h | |
Organ | |||||||
 Blood | 4.05 ± 1.06 | 1.44 ± 0.35 | 0.05 ± 0.01 | 0.04 ± 0.02 | 0.03 ± 0.03 | 0.07 ± 0.02 | 0.09 ± 0.02 |
 Brain | 0.94 ± 0.21 | 0.11 ± 0.01 | 0.02 ± 0.02 | 0.01 ± 0.01 | 0.01 ± 0.00 | 0.06 ± 0.01 | 0.04 ± 0.02 |
 Heart | 2.20 ± 0.38 | 0.47 ± 0.11 | 0.24 ± 0.16 | 0.06 ± 0.05 | 0.04 ± 0.04 | 0.11 ± 0.03 | 0.15 ± 0.05 |
 Lungs | 5.82 ± 4.34 | 1.35 ± 0.18 | 0.36 ± 0.17 | 0.27 ± 0.09 | 0.08 ± 0.10 | 0.16 ± 0.03 | 0.19 ± 0.04 |
 Liver | 19.81 ± 0.38 | 4.12 ± 0.30 | 1.53 ± 0.25 | 0.82 ± 0.28 | 0.46 ± 0.48 | 1.35 ± 0.20 | 1.52 ± 0.25 |
 Spleen | 4.06 ± 1.50 | 0.87 ± 0.09 | 0.39 ± 0.26 | 0.33 ± 0.30 | 0.05 ± 0.06 | 0.34 ± 0.15 | 0.11 ± 0.02 |
 Kidney | 5.87 ± 1.74 | 1.14 ± 0.15 | 0.18 ± 0.07 | 0.11 ± 0.04 | 0.05 ± 0.03 | 0.61 ± 0.53 | 0.17 ± 0.01 |
 Stomach | 5.22 ± 1.55 | 2.24 ± 1.43 | 0.08 ± 0.02 | 0.11 ± 0.10 | 0.05 ± 0.03 | 0.17 ± 0.09 | 0.51 ± 0.28 |
 Large intestine | 3.43 ± 0.52 | 0.72 ± 0.36 | 0.11 ± 0.06 | 0.06 ± 0.06 | 0.05 ± 0.06 | 0.29 ± 0.07 | 0.17 ± 0.04 |
 Small intestine | 3.56 ± 0.40 | 0.79 ± 0.47 | 0.05 ± 0.01 | 0.05 ± 0.03 | 0.02 ± 0.01 | 0.38 ± 0.18 | 0.18 ± 0.03 |
 Muscle | 1.18 ± 0.33 | 0.28 ± 0.03 | 0.02 ± 0.02 | 0.01 ± 0.00 | 0.02 ± 0.01 | 0.07 ± 0.02 | 0.17 ± 0.04 |
 Bone | 3.24 ± 1.50 | 0.65 ± 0.08 | 0.12 ± 0.03 | 0.56 ± 0.89 | 0.04 ± 0.07 | 0.16 ± 0.01 | 0.17 ± 0.05 |
 Tumor | 16.37 ± 3.32 | 14.33 ± 3.30 | 7.41 ± 2.21 | 4.26 ± 1.36 | 3.31 ± 1.45 | 2.67 ± 1.16 | 0.15 ± 0.12 |
 Thyroid | 6.51 ± 2.13 | 1.36 ± 0.17 | 0.11 ± 0.04 | 0.08 ± 0.05 | 0.04 ± 0.06 | 0.29 ± 0.08 | 0.25 ± 0.02 |
 Eyes | 22.45 ± 4.74 | 15.02 ± 2.12 | 11.27 ± 0.90 | 9.77 ± 1.02 | 7.17 ± 0.96 | 4.66 ± 1.10 | 0.30 ± 0.02 |
Uptake ratio | |||||||
 Tumor-to-blood | 4.16 ± 0.74 | 10.04 ± 0.75 | 151.3 ± 64.35 | 132.9 ± 124.9 | 188.1 ± 110.9 | 50.56 ± 40.23 | 1.49 ± 1.02 |
 Tumor-to-liver | 0.85 ± 0.18 | 3.47 ± 0.70 | 4.91 ± 1.65 | 5.45 ± 2.16 | 10.49 ± 5.01 | 1.96 ± 0.73 | 0.10 ± 0.07 |
 Tumor-to-muscle | 14.53 ± 3.33 | 51.72 ± 13.58 | 248.4 ± 143.7 | 121.5 ± 66.76 | 123.4 ± 37.89 | 40.08 ± 16.20 | 0.82 ± 0.29 |