Fig. 7From: Kinase inhibitor library screening identifies synergistic drug combinations effective in sensitive and resistant melanoma cellsPathways affected by the combined selected kinase inhibitors in BRAF mutant melanoma cells. Scheme summarizing the effects of cell cycle-influencing proteins targeted by the identified kinase inhibitors (black boxes). The pathway on the right (grey background) represents mitogenic factor-induced or mutated BRAF-induced entry into the cell cycle, while the left box (blue background) depicts players involved in progression through the different checkpoints and phases of the cell cycle. cdc25: cell division cycle 25Back to article page