circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

Table 1 Clinicopathological variables and circGFRA1 expression in 222 breast cancer patients

Variables	Cases (n = 222)	circGFRA1				P value
Variables	Cases (n = 222)	Low		High		P value
Age (years)						0.216
≤ 50	148	73	49.3%	75	50.7%
> 50	74	30	40.5%	44	59.5%
menopause						0.738
no	131	62	47.3%	69	52.7%
yes	91	41	45.1%	50	54.9%
Tumor size (cm)						0.029*
≤ 2	70	40	57.1%	30	42.9%
> 2	152	63	41.4%	89	58.6%
TNM Staging						<0.001*
I-II	155	93	60.0%	62	40.0%
III-IV	67	10	14.9%	57	85.1%
LN Infiltrated						<0.001*
No	117	87	74.4%	30	25.6%
Yes	105	16	15.2%	89	84.8%
Histological grade						0.036*
Well differentiated	2	2	100.0%	0	0.0%
Moderately differentiated	109	57	52.3%	52	47.7%
Poorly differentiated	111	44	39.6%	67	60.4%

ISSN: 1756-9966