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Table 2 The correlations between clinicopathological characteristics and overall survival or recurrence-free survival of SCC patients using the Kaplan-Meier method

From: Extracellular vesicular Wnt7b mediates HPV E6-induced cervical cancer angiogenesis by activating the β-catenin signaling pathway

Variable

Overall Survival (months)

Mean ± SE

P

Recurrence- Free Survival (months)

Mean ± SE

P

Age, y (mean ± SD)

0.073

 

0.058

  < =45

57.21 ± 1.75

 

57.07 ± 1.89

 

  > 45

52.75 ± 1.87

 

51.32 ± 2.12

 

Stage

 

0.060

 

0.107

 I

56.18 ± 1.41

 

55.03 ± 1.69

 

 II

48.17 ± 3.31

 

47.27 ± 3.60

 

Tumor size

 

0.098

 

0.170

  < =4 cm

55.56 ± 1.61

 

54.41 ± 1.87

 

  > 4 cm

50.55 ± 2.94

 

49.61 ± 3.21

 

Lymphovascular invasion

0.023

 

0.052

 Negative

57.05 ± 1.36

 

55.68 ± 1.86

 

 Positive

51.48 ± 2.25

 

50.53 ± 2.48

 

Stromal invasion depth

0.067

 

0.058

  < 1/2

57.60 ± 1.67

 

57.28 ± 1.89

 

  > =1/2

51.52 ± 2.00

 

50.11 ± 2.25

 

Lymph node metastasis

< 0.001

 

< 0.001

 Negative

57.71 ± 0.74

 

57.49 ± 0.86

 

 Positive

44.29 ± 3.86

 

41.29 ± 4.28

 

Parametrial invasion

0.228

 

0.027

 Negative

56.65 ± 1.47

 

54.06 ± 1.62

 

 Positive

46.86 ± 6.65

 

39.86 ± 7.81

 

Margin

 

0.531

 

0.573

 Negative

54.41 ± 1.48

 

53.34 ± 1.67

 

 Positive

48.25 ± 7.58

 

47.00 ± 8.66

 

Serum EV-Wnt 7b

 

< 0.001

 

< 0.001

 Low

58.43 ± 0.56

 

58.35 ± 0.64

 

 High

49.00 ± 2.69

 

46.90 ± 3.02