Fig. 7

Cirbp silencing-induced sensitization of subcutaneous tumor xenografts to hyperthermia by local thermal ablation with ICG and an NIR laser in vivo. A Schematic representation of the experimental design of hyperthermia treatment in nude mice harboring subcutaneous tumor xenografts formed by CNE2 or HONE1-EBV cells. B, E Representative images of stripped xenograft tumors formed by CNE2 B and HONE1-EBV E cells at the end of hyperthermia therapy (n = 3-4 mice/group). C, F The tumor growth curve (n = 3-4 mice/group). D, G Tumor weight (n = 3-4 mice/group). H Representative pictures of H&E staining of stripped xenograft tumors (showed in Fig. 7B, E)