Fig. 8

Ectopic expression of Cirbp counteracted the tumor-killing effect of hyperthermia on NPC cells and cancer stem-like cells in vivo. A Schematic representation of the experimental design of hyperthermia treatment in nude mice bearing subcutaneous tumor xenografts formed by CNE2 or SUNE1 cells. B, E Representative images of stripped xenograft tumors formed by CNE2 B and SUNE1 E cells at the end of hyperthermia therapy (n = 4 mice/group). C, F The tumor growth curve (n = 4 mice/group). D, G Tumor weight (n = 4 mice/group). H Representative pictures of H&E staining of stripped xenograft tumors (showed in Fig. 8B,E)